Influence of brain-derived neurotrophic-factor and apolipoprotein E genetic variants on hippocampal volume and memory performance in healthy young adults

@article{RichterSchmidinger2010InfluenceOB,
  title={Influence of brain-derived neurotrophic-factor and apolipoprotein E genetic variants on hippocampal volume and memory performance in healthy young adults},
  author={Tanja Richter-Schmidinger and Panagiotis Alexopoulos and Marco Antonio Horn and Sebastian Maus and M Reichel and Cosima Rhein and Piotr Lewczuk and Christos Sidiropoulos and Thomas Kneib and Robert Perneczky and Arnd Doerfler and Johannes Kornhuber},
  journal={Journal of Neural Transmission},
  year={2010},
  volume={118},
  pages={249-257}
}
Unravelling the impact of genetic variants on clinical phenotypes is a challenging task. Apolipoprotein E (ApoE) and brain-derived neurotrophic factor (BDNF) play an important role in cell growth, regeneration, synaptic plasticity, learning and memory processes. The aim of the present study was to examine the impact of BDNF Val66Met- and ApoE-polymorphisms and their interactions on hippocampal morphology and memory functions in healthy young adults. Hippocampal volume and memory performance of… CONTINUE READING

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IGD. Inventar zur Gedächtnisdiagnostik

  • G Baller, M Brand, E Kalbe, J Kessler
  • Hofgrefe Verlag GmbH & Co. KG,
  • 2006
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