Influence of bone morphogenetic protein-2 on the extracellular matrix, material properties, and gene expression of long-term articular chondrocyte cultures: loss of chondrocyte stability.

Abstract

The aim of this study was to determine the effects of bone morphogenetic protein-2 (BMP-2) on articular chondrocyte tissues grown as monolayers in vitro for up to 8 weeks. Articular chondrocytes were isolated from New Zealand White rabbits and plated in monolayer cultures. The cultures were supplemented with 100 ng/mL of BMP-2 for up to 8 weeks and the… (More)
DOI: 10.1089/ten.tea.2008.0249

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@article{Krawczak2009InfluenceOB, title={Influence of bone morphogenetic protein-2 on the extracellular matrix, material properties, and gene expression of long-term articular chondrocyte cultures: loss of chondrocyte stability.}, author={David A Krawczak and Jennifer J. Westendorf and Cathy Sue Carlson and J. Lewis}, journal={Tissue engineering. Part A}, year={2009}, volume={15 6}, pages={1247-55} }