Influence of body mass index on outcome in advanced colorectal cancer patients receiving chemotherapy with or without targeted therapy.

@article{Simkens2011InfluenceOB,
  title={Influence of body mass index on outcome in advanced colorectal cancer patients receiving chemotherapy with or without targeted therapy.},
  author={Lieke H. J. Simkens and Miriam Koopman and Linda Mol and Gerrit Jan Veldhuis and Daan ten Bokkel Huinink and Erik W. Muller and Veerle A. Derleyn and Steven Teerenstra and Cornelis J A Punt},
  journal={European journal of cancer},
  year={2011},
  volume={47 17},
  pages={2560-7}
}
PURPOSE Obesity is associated with an increased risk of development and recurrence of colorectal cancer. However, the role of obesity in advanced colorectal cancer (ACC) patients is unknown. We investigated the effect of body mass index (BMI) on overall survival (OS) in ACC patients receiving systemic treatment in two large phase III studies (CAIRO and CAIRO2). PATIENTS AND METHODS Treatment data were obtained and analysed from 796 ACC patients who were treated with chemotherapy in the CAIRO… CONTINUE READING