Influence of blocking of 2,3-butanediol pathway on glycerol metabolism for 1,3-propanediol production by Klebsiella oxytoca.

@article{Zhang2012InfluenceOB,
  title={Influence of blocking of 2,3-butanediol pathway on glycerol metabolism for 1,3-propanediol production by Klebsiella oxytoca.},
  author={Gang Zhang and Guang Yang and Xu Wang and Qingjuan Guo and Ying Li and Jilun Li},
  journal={Applied biochemistry and biotechnology},
  year={2012},
  volume={168 1},
  pages={116-28}
}
Glycerol metabolism is a typical biological oxidoreductive reaction. 1,3-Propanediol (1,3-PD) is the final product of the reductive branch, while acetate, succinate, lactate, 2,3-butanediol (2,3-BD), and ethanol were produced in the oxidative branch. 2,3-BD, which has similar properties of high boiling point and water solubility with 1,3-PD, not only contests the carbon flow and NADH with 1,3-PD but also serves as an obstacle for obtaining high purity 1,3-PD in downstream processes. In this… CONTINUE READING
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