Influence of beta-casomorphins on apomorphine-induced hyperlocomotion.


Derivatives of beta-casomorphin Tyr-Pro-Phe-Pro-Gly and their des-Tyr1-derivatives were investigated on the model of apomorphine-induced hyperlocomotion (1 mg/kg = 3 microM/kg, IP). D-Pip4 CM 5 (5 nM) inhibited the apomorphine hypermotility completely, while D-Phe3 CM 5 (5 nM) and D-Pro4 CM 5 (5 nM) decreased it only to about 50%. The normal exploration was… (More)


Cite this paper

@article{Ruethrich1993InfluenceOB, title={Influence of beta-casomorphins on apomorphine-induced hyperlocomotion.}, author={H L Ruethrich and Gisela Grecksch and Hansj{\"{u}rgen Matthies}, journal={Pharmacology, biochemistry, and behavior}, year={1993}, volume={44 1}, pages={227-31} }