Influence of beta-adrenoceptor agonists and antagonists on baclofen-induced memory impairment in mice.

@article{Zarrindast2004InfluenceOB,
  title={Influence of beta-adrenoceptor agonists and antagonists on baclofen-induced memory impairment in mice.},
  author={Mohammad Reza Zarrindast and Homa Haidari and Mohammad Reza Jafari and Bijan Djahanguiri},
  journal={Behavioural pharmacology},
  year={2004},
  volume={15 4},
  pages={293-7}
}
Post-training administration of different doses of baclofen (a GABAB agonist) has been shown to impair memory retention, in a step-down passive avoidance test in mice. We have studied the effects of beta-adrenergic agonists and antagonists on baclofen-induced memory impairment in mice. Dobutamine (a beta 1-agonist) or salbutamol (a beta 2-agonist) reversed the memory impairment induced by baclofen without exhibiting intrinsic actions on memory when administered alone. The administration of… CONTINUE READING

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