Influence of atopic heredity on IL-4-, IL-12- and IFN-gamma-producing cells in in vitro activated cord blood mononuclear cells.

@article{Gabrielsson2001InfluenceOA,
  title={Influence of atopic heredity on IL-4-, IL-12- and IFN-gamma-producing cells in in vitro activated cord blood mononuclear cells.},
  author={Susanne Gabrielsson and Atle S{\"o}derlund and Caroline Nilsson and G. Patrick Lilja and Markus Nordlund and Marita Troye-Blomberg},
  journal={Clinical and experimental immunology},
  year={2001},
  volume={126 3},
  pages={390-6}
}
Several reports have claimed that there is a greater risk for a child with an atopic mother to develop allergy as compared to a child with an atopic father. This suggests that the fetal environment during pregnancy might be of importance for the development of atopic disease. Both proliferative and cytokine responses have been detected in cord blood mononuclear cells (CBMC) after stimulation with allergens, suggesting allergen priming already in utero. The aim of this study was to investigate… CONTINUE READING

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