Influence of apolipoprotein E genotype on blood redox status of Alzheimer's disease patients.

@article{Fernandes1999InfluenceOA,
  title={Influence of apolipoprotein E genotype on blood redox status of Alzheimer's disease patients.},
  author={Maria Augusta Fernandes and Maria Teresa Proença and Ant{\'o}nio J. A. Nogueira and Manuela M. Grazina and Leila M Oliveira and Ana Isabel Fernandes and Beatriz Hern{\'a}ndez Santiago and Isabel Santana and Catarina Resende de Oliveira},
  journal={International journal of molecular medicine},
  year={1999},
  volume={4 2},
  pages={179-86}
}
The blood redox status of probable Alzheimer's Disease (AD) patients and control subjects with distinct Apo E genotypes was investigated. It was assessed by measuring the levels of hydroperoxides (MDA) in plasma and erythrocytes, the levels of the antioxidant defense system (enzymatic and non-enzymatic) in plasma, erythrocytes, platelets and leukocytes, the activities of catechol-O-methyltransferase (COMT) in erythrocytes and monoamine oxidase-B (MAO-B) in platelets and also the activity of the… CONTINUE READING

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