Influence of anticholinergic activity in serum on clinical symptoms of Alzheimer's disease.

@article{Hori2011InfluenceOA,
  title={Influence of anticholinergic activity in serum on clinical symptoms of Alzheimer's disease.},
  author={Koji Hori and Kimiko Konishi and Koichiro Watanabe and Hiroyuki Uchida and Takashi Tsuboi and Matsuko Moriyasu and Itaru Tominaga and Mitsugu Hachisu},
  journal={Neuropsychobiology},
  year={2011},
  volume={63 3},
  pages={147-53}
}
Alzheimer's disease (AD) is well known as a disease characterized by degeneration of cholinergic neuronal activity in the brain. It follows that patients with AD would be sensitive to an 'anticholinergic burden', and also that medicine with anticholinergic properties would promote various clinical symptoms of AD. Despite the relevance of this important phenomenon to the clinical therapeutics of AD patients, few reports have been seen concerning the relationship between anticholinergic burden… CONTINUE READING