Influence of antibiotics on lymphocyte function in vitro

  title={Influence of antibiotics on lymphocyte function in vitro},
  author={Prof. Dr. A. Forsgren and Dr. G. Banck},
The effect of 20 different antibiotics on the incorporation of3H-thymidine by human peripheral T-lymphocytes in serum-free medium stimulated by PHA was studied. Of the antibiotics tested fusidic acid and rifampin had a pronounced inhibiting effect at therapeutic concentrations. At concentrations above the therapeutic level a marked inhibiting effect was detected for tetracyclines, erythromycin, clindamycin and nitrofurantoin. No apparent inhibiting effect on the PHA-response of human… CONTINUE READING