Influence of androgen deprivation therapy on all-cause mortality in men with high-risk prostate cancer and a history of congestive heart failure or myocardial infarction.

@article{Nguyen2012InfluenceOA,
  title={Influence of androgen deprivation therapy on all-cause mortality in men with high-risk prostate cancer and a history of congestive heart failure or myocardial infarction.},
  author={Paul Linh Nguyen and Ming-Hui Chen and Joshua A Beckman and Clair J. Beard and Neil E. Martin and Toni K Choueiri and Jim C Hu and Karen Elizabeth Hoffman and Daniel E. Dosoretz and Brian Joseph Moran and Sharon A. Salenius and Michelle H. Braccioforte and Philip W. Kantoff and Anthony V. D'Amico and Ronald D. Ennis},
  journal={International journal of radiation oncology, biology, physics},
  year={2012},
  volume={82 4},
  pages={
          1411-6
        }
}
PURPOSE It is unknown whether the excess risk of all-cause mortality (ACM) observed when androgen deprivation therapy (ADT) is added to radiation for men with prostate cancer and a history of congestive heart failure (CHF) or myocardial infarction (MI) also applies to those with high-risk disease. METHODS AND MATERIALS Of 14,594 men with cT1c-T3aN0M0 prostate cancer treated with brachytherapy-based radiation from 1991 through 2006, 1,378 (9.4%) with a history of CHF or MI comprised the study… CONTINUE READING
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