Influence of an acidic beverage (Coca-Cola) on the absorption of itraconazole

Abstract

Objective: To evaluate the effectiveness of Coca-Cola in enhancing the absorption of itraconazole. Methods: Eight healthy volunteers were randomized to receive two treatment sequences in a two-way crossover design with a 1-week wash-out period separating each study treatment. Treatment I, the control, consisted of 100 mg itraconazole with 325 ml water… (More)
DOI: 10.1007/s002280050280

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