Influence of ammonium ions on mechanical and electrophysiological responses of skeletal muscle.

@article{Heald1975InfluenceOA,
  title={Influence of ammonium ions on mechanical and electrophysiological responses of skeletal muscle.},
  author={D E Heald},
  journal={The American journal of physiology},
  year={1975},
  volume={229 5},
  pages={1174-9}
}
  • D E Heald
  • Published 1975 in The American journal of physiology
Substitution of ammonium ions for sodium ion initially potentiated and then depressed twitch tension of the frog sartorius muscle. The extent of potentiation and the rate of depression of the twitch were dependent upon the concentration of ammonium ions. Ammonium ion depolarized individual muscle fibers in proportion to concentration. Maximum depolarization (33 mV) occurred in muscles equilibrated in 120 mM ammonium-Ringer for 30 min. At the higher concentration of ammonium (72--120 mM), the… CONTINUE READING
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