Influence of aminoglutethimide on plasma levels of medroxyprogesterone acetate: its correlation with serum cortisol.

Abstract

Postmenopausal patients with metastatic breast cancer were treated with aminoglutethimide (AG) and high-dose medroxyprogesterone acetate (MPA). Studying the interaction between the two drugs as far as plasma MPA and cortisol levels are concerned we observed a 50% decrease of plasma MPA levels after the addition of AG (P less than 0.005). With large… (More)

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@article{Deijk1985InfluenceOA, title={Influence of aminoglutethimide on plasma levels of medroxyprogesterone acetate: its correlation with serum cortisol.}, author={W A van Deijk and Geert H. Blijham and Wilhelmina A M Mellink and P M Meulenberg}, journal={Cancer treatment reports}, year={1985}, volume={69 1}, pages={85-90} }