Influence of alpha- and beta-adrenoceptor antagonists on ventricular fibrillation in ischemic rat hearts

@article{Toelg1997InfluenceOA,
  title={Influence of alpha- and beta-adrenoceptor antagonists on ventricular fibrillation in ischemic rat hearts},
  author={Ralph Toelg and Thomas Kurz and Martin Ungerer and Juergen Schreieck and Bettina G{\"o}rge and Gert Richardt},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={1997},
  volume={356},
  pages={62-68}
}
Although it is generally accepted that adrenergic influences contribute to arrhythmias during myocardial ischemia, it is still a matter of debate whether these arrhythmogenic effects are mediated via alpha- or beta-adrenergic receptors and which particular receptor subtype is involved. Controversial results may be due to ancillary properties of the adrenergic receptor antagonists used to resolve this question. Therefore, we compared the influence of various, structurally different alpha- and… CONTINUE READING

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