Influence of alcohol on the hemodynamic effects and pharmacokinetic properties of mirodenafil: A single-dose, randomized-sequence, open-label, crossover study in healthy male volunteers in Korea

@article{Kim2009InfluenceOA,
  title={Influence of alcohol on the hemodynamic effects and pharmacokinetic properties of mirodenafil: A single-dose, randomized-sequence, open-label, crossover study in healthy male volunteers in Korea},
  author={Bo-Hyung Kim and S Yi and Jaewoo Kim and Kyoung Soo Lim and Kyu-pyo Kim and Bongyong Lee and S Shin and I. C. Jang and Kyung-Sang Yu},
  journal={Clinical therapeutics},
  year={2009},
  volume={31 6},
  pages={
          1234-43
        }
}
BACKGROUND Mirodenafil is a phosphodiesterase type 5 (PDE-5) inhibitor developed for the treatment of erectile dysfunction. Mirodenafil has the possibility of being administered with alcohol. OBJECTIVE This study assessed the hemodynamic effects and pharmacokinetic properties of mirodenafil administered with alcohol. METHODS This single-dose, randomized-sequence, open-label, crossover study was conducted in healthy male volunteers at the Clinical Trials Center, Seoul National University… CONTINUE READING
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