Influence of aging on the synthesis and morphology of the aggrecans synthesized by differentiated human articular chondrocytes.

Abstract

OBJECTIVE Synthesis rates of aggrecans by phenotypically stable human articular chondrocytes and the immobilization of these aggrecans in large aggregates were used as variables reflecting the capability of these cells of restoring the extracellular matrix of articular cartilage in vivo in an aging population. DESIGN Human articular chondrocytes were… (More)

Topics

Cite this paper

@article{Verbruggen2000InfluenceOA, title={Influence of aging on the synthesis and morphology of the aggrecans synthesized by differentiated human articular chondrocytes.}, author={Gust Verbruggen and M. J. W. J. Cornelissen and K. F. Almqvist and L Wang and Dirk Elewaut and C. Broddelez and L de Ridder and Eric M. Veys}, journal={Osteoarthritis and cartilage}, year={2000}, volume={8 3}, pages={170-9} }