This project is aimed to estimate the effect of passive smoke on the levels of selected trace elements (Ca, Mg, K, Na) in pharyngeal tonsils of children in several group of age (2-5 years, 6-9 years, 10-15 years). This trace elements were determined using ICP-AES method. It was concluded that the exposure to the cigarette smoke in pharyngeal tonsils is a factor producing the changes in the levels of essential elements: geometric mean of Ca was the highest in pharyngeal tonsils of children in 10-15 years old unexposure to ETS (410 microg/g). The least level of Ca - 281 microg/g was observed in this samples in the same group of age, but in children exposure by ETS. High levels of K was observed in pharyngeal tonsils of children exposure to passive smoking in all of group of age to comparison to unexposure by ETS. The greatest content - 27479 microg/g was in pharyngeal tonsils in exposure to ETS in 6-9 years old was observed, but the least - 16478 microg/g in 10-15 years old. Change of content of Mg was from 764 to 784 microg/g in samples from children exposure by ETS to comparison 720-744 microg/g in children unexposure by ETS. High level of Na was observed in pharyngeal tonsils from children exposure to ETS in all of group of age to comparison to unexposure. This study showed that the kind of interaction dependent on age and exposed by ETS. The changes of given elements were different for children passive smoking and no passive smoking in several group of age.