Influence of age and sex on serum complement components in children.

  title={Influence of age and sex on serum complement components in children.},
  author={Brendan Roach and Yong Ku Kim and Elizabeth Heidi Jerome and Alfred F. Michael},
  journal={American journal of diseases of children},
  volume={135 10},
Concentrations of eight complement components were determined on sera from 419 healthy children (198 boys and 221 girls) aged from 1 to 19 years. A significant correlation between concentration and age for all complement components (C1q, C1s, C4, C3, C5, factor B, properdin, and C1 inhibitor) was observed for girls; in the male population, a significant correlation was present only for C1q, C4, C3, C5, and properdin. The presence of a significant relationship to age suggests that this variable… CONTINUE READING

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