Influence of age, sex, and strength training on human muscle gene expression determined by microarray.

@article{Roth2002InfluenceOA,
  title={Influence of age, sex, and strength training on human muscle gene expression determined by microarray.},
  author={Stephen M Roth and Robert E. Ferrell and David G. Peters and E. Jeffrey Metter and Ben F. Hurley and Marc A Rogers},
  journal={Physiological genomics},
  year={2002},
  volume={10 3},
  pages={181-90}
}
The purpose of this study was to determine the influence of age, sex, and strength training (ST) on large-scale gene expression patterns in vastus lateralis muscle biopsies using high-density cDNA microarrays and quantitative PCR. Muscle samples from sedentary young (20-30 yr) and older (65-75 yr) men and women (5 per group) were obtained before and after a 9-wk unilateral heavy resistance ST program. RNA was hybridized to cDNA filter microarrays representing approximately 4,000 known human… CONTINUE READING

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Proceedings of the National Academy of Sciences of the United States of America • 2001
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