Influence of a positive family history of both type 2 diabetes and PCOS on metabolic and endocrine parameters in a large cohort of PCOS women.

@article{Lerchbaum2014InfluenceOA,
  title={Influence of a positive family history of both type 2 diabetes and PCOS on metabolic and endocrine parameters in a large cohort of PCOS women.},
  author={E. Lerchbaum and V. Schwetz and A. Giuliani and B. Obermayer-Pietsch},
  journal={European journal of endocrinology},
  year={2014},
  volume={170 5},
  pages={
          727-39
        }
}
OBJECTIVE There is evidence suggesting a strong genetic background of polycystic ovary syndrome (PCOS). We aim to study the metabolic and endocrine characteristics of PCOS women with and without a family history (FHx) of type 2 diabetes mellitus (T2DM) and PCOS. DESIGN Cross-sectional study. METHODS We analysed the association of T2DM FHx and PCOS FHx with metabolic and endocrine parameters in 714 PCOS women. RESULTS A positive FHx of T2DM and PCOS were prevalent in 36.8 and 21.4% of PCOS… Expand
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