Influence of a functional polymorphism within the angiotensin I-converting enzyme gene on partial sleep deprivation in patients with major depression.

@article{Baghai2003InfluenceOA,
  title={Influence of a functional polymorphism within the angiotensin I-converting enzyme gene on partial sleep deprivation in patients with major depression.},
  author={Thomas C. Baghai and Cornelius Schule and Peter Zwanzger and Peter Zill and Robin Ella and Daniela Eser and Tobias Deiml and Christo Minov and Rainer Rupprecht and Brigitta Bondy},
  journal={Neuroscience letters},
  year={2003},
  volume={339 3},
  pages={223-6}
}
Partial sleep deprivation (PSD) exerts transient antidepressant efficacy. As a potential mechanism of action an enhancement of dopaminergic neurotransmission within the CNS is discussed. Because genetic variations influencing neurotransmission could have an impact on therapeutic outcome and stability of improvement, we investigated the functional insertion… CONTINUE READING