Influence of a Streptomyces lividans SecG functional analogue on protein secretion.

@article{Palomino2008InfluenceOA,
  title={Influence of a Streptomyces lividans SecG functional analogue on protein secretion.},
  author={Carmen Palomino and Rafael P. Mellado},
  journal={International microbiology : the official journal of the Spanish Society for Microbiology},
  year={2008},
  volume={11 1},
  pages={25-31}
}
The membrane protein complex translocase mediates the translocation of bacterial proteins. In this complex, the SecY, SecE, and SecG proteins constitute an integral membrane domain. Sequence comparison revealed a potential secG-like gene in the gram-positive soil bacterium Streptomyces lividans. Chromosomal deletion of this gene resulted in a sporulation defect and an overall deficiency in secretion. The SecG-depleted strain was able to overproduce and secrete alpha-amylase, but the appearance… CONTINUE READING

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