Influence of Withania somnifera on obsessive compulsive disorder in mice.

@article{Kaurav2012InfluenceOW,
  title={Influence of Withania somnifera on obsessive compulsive disorder in mice.},
  author={Bhanu P S Kaurav and M. Wanjari and A. Chandekar and Nagendra Singh Chauhan and N. Upmanyu},
  journal={Asian Pacific journal of tropical medicine},
  year={2012},
  volume={5 5},
  pages={
          380-4
        }
}
OBJECTIVE To study the influence of methanolic and aqueous extract of Withania somnifera (W. somnifera) root on the marble-burying behavior of mice a well-accepted model of obsessive compulsive behavior. METHODS Mice were divided in different groups (n = 6). Fluoxetine (5, 10, 15 mg/kg), (10, 25, 50, 100 mg/kg) and methanolic extract W. somnifera (MEWS) (10, 25, 50, 100 mg/kg) were administered i.p. 30 min. prior to the assessment of marble burying behavior and locomotor activity. The control… Expand
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