Influence of Trigger PSA and PSA Kinetics on 11C-Choline PET/CT Detection Rate in Patients with Biochemical Relapse After Radical Prostatectomy

@article{Castellucci2009InfluenceOT,
  title={Influence of Trigger PSA and PSA Kinetics on 11C-Choline PET/CT Detection Rate in Patients with Biochemical Relapse After Radical Prostatectomy},
  author={Paolo Castellucci and Chiara Fuccio and Cristina Nanni and Ivan Santi and Anna Rizzello and Filippo Lodi and Alessandro Franceschelli and Giuseppe Sigismondo Martorana and Fabio Manferrari and Stefano Fanti},
  journal={Journal of Nuclear Medicine},
  year={2009},
  volume={50},
  pages={1394 - 1400}
}
The purpose of this study was to investigate the effect of total prostate-specific antigen (PSA) at the time of 11C-choline PET/CT (trigger PSA), PSA velocity (PSAvel), and PSA doubling time (PSAdt) on 11C-choline PET/CT detection rate in patients treated with radical prostatectomy for prostate cancer, who showed biochemical failure during follow-up. Methods: A total of 190 patients treated with radical prostatectomy for prostate cancer who showed an increase in PSA (mean, 4.2; median, 2.1… 

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