Influence of Time and Temperature on Coagulation Analytes in Stored Plasma

  title={Influence of Time and Temperature on Coagulation Analytes in Stored Plasma},
  author={W. Heil and R. Grunewald and M. Amend and M. Heins},
  booktitle={Clinical chemistry and laboratory medicine},
  • W. Heil, R. Grunewald, +1 author M. Heins
  • Published in
    Clinical chemistry and…
  • Chemistry, Medicine
  • Abstract There is no comprehensive study on the stability of coagulation analytes in plasma. We therefore determined the influence of storage time and temperature on prothrombin time, activated partial thromboplastin time, thrombin time, fibrinogen, factors V and VIII, antithrombin III, protein C and S in plasma from 20 healthy subjects and 20 patients receiving heparin therapy. The stability in plasma, defined as the period during which there was a change of less than 10 % from the initial… CONTINUE READING
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