Influence of Sulfation on Platelet Aggregation and Activation with Differentially Sulfated Hyaluronic Acids

@article{Barbucci1998InfluenceOS,
  title={Influence of Sulfation on Platelet Aggregation and Activation with Differentially Sulfated Hyaluronic Acids},
  author={Rolando Barbucci and Stefania Lamponi and Agnese Magnani and Lawrence F. Poletti and Nick P. Rhodes and Michael Sobel and David F Williams},
  journal={Journal of Thrombosis and Thrombolysis},
  year={1998},
  volume={6},
  pages={109-115}
}
A number of sulfated hyaluronic acid derivatives (HyalS2.5, HyalS3, and HyalS4) were prepared by sulfation of the -OH groups present on hyaluronic acid and were generically termed HyalSx. The anticoagulant properties of this series of compounds has previously been shown to be good in terms of their whole blood clotting inhibition and factor Xa and thrombin… CONTINUE READING