Influence of Sex and Estrogen on Musculotendinous Protein Turnover at Rest and After Exercise

  title={Influence of Sex and Estrogen on Musculotendinous Protein Turnover at Rest and After Exercise},
  author={M. Hansen and M. Kjaer},
  journal={Exercise and Sport Sciences Reviews},
  • M. Hansen, M. Kjaer
  • Published 2014
  • Medicine
  • Exercise and Sport Sciences Reviews
  • Women differ from men with regard to muscle and tendon, most likely because of sex differences in estrogen. The present experimental findings suggest the hypothesis that estrogen has an anabolic effect on muscle primarily by lowering the protein turnover and enhancing sensitivity to resistance training. Furthermore, estrogen may reduce the stiffness of tendons, an effect that may be modified by physical training. 
    48 Citations
    Female hormones: do they influence muscle and tendon protein metabolism?
    • M. Hansen
    • Medicine
    • The Proceedings of the Nutrition Society
    • 2018
    • 25
    • PDF
    Effect of Estrogen on Musculoskeletal Performance and Injury Risk
    • 28
    • Highly Influenced
    • PDF
    The effect of estrogen on tendon and ligament metabolism and function
    • 26
    Impact of oestrogen deficiency and aging on tendon: concise review.
    • 30
    • PDF
    Human COL5A1 polymorphisms and quadriceps muscle–tendon mechanical stiffness in vivo
    • 6


    Hormone therapy is associated with smaller Achilles tendon diameter in active post‐menopausal women
    • 78
    Estrogen replacement, muscle composition, and physical function: The Health ABC Study.
    • 61
    Effects of estrogen replacement and lower androgen status on skeletal muscle collagen and myofibrillar protein synthesis in postmenopausal women.
    • 25
    • Highly Influential
    • PDF
    Effect of estrogen on tendon collagen synthesis, tendon structural characteristics, and biomechanical properties in postmenopausal women.
    • 103
    • PDF
    Higher muscle protein synthesis in women than men across the lifespan, and failure of androgen administration to amend age‐related decrements
    • G. Henderson, K. Dhatariya, +7 authors K. Nair
    • Biology, Medicine
    • FASEB journal : official publication of the Federation of American Societies for Experimental Biology
    • 2009
    • 90
    Tendon collagen synthesis at rest and after exercise in women.
    • 144
    • PDF
    Effect of acute resistance exercise and sex on human patellar tendon structural and regulatory mRNA expression.
    • 56
    • PDF
    Testosterone and progesterone, but not estradiol, stimulate muscle protein synthesis in postmenopausal women.
    • 54
    • Highly Influential
    • PDF
    Estrogen supplementation reduces whole body leucine and carbohydrate oxidation and increases lipid oxidation in men during endurance exercise.
    • 95
    • PDF
    Impact of sex and chronic resistance training on human patellar tendon dry mass, collagen content, and collagen cross-linking.
    • 32
    • PDF