Influence of Psychological Factors on Risk of Temporomandibular Disorders

@article{Slade2007InfluenceOP,
  title={Influence of Psychological Factors on Risk of Temporomandibular Disorders},
  author={Gary D. Slade and Luda Diatchenko and Konakporn Bhalang and A Sigurdsson and Roger Benton Fillingim and Inna Belfer and Mitchell B. Max and David Goldman and William Maixner},
  journal={Journal of Dental Research},
  year={2007},
  volume={86},
  pages={1120 - 1125}
}
Psychological characteristics potentially may be a cause or consequence of temporomandibular disorder (TMD). We hypothesized that psychological characteristics associated with pain sensitivity would influence risk of first-onset TMD, but the effect could be attributed to variation in the gene encoding catechol-O-methyltransferase (COMT). We undertook a prospective cohort study of healthy female volunteers aged 18–34 yrs. At baseline, participants were genotyped, they completed psychological… 
Psychological factors associated with development of TMD: the OPPERA prospective cohort study.
COMT Diplotype Amplifies Effect of Stress on Risk of Temporomandibular Pain
TLDR
It is hypothesized that temporal escalation in stress exacerbates risk for TMD, and the effect is amplified by allelic variants in a gene, catechol-O-methyltransferase (COMT), regulating catechl neurotransmitter catabolism.
Depressive and anxiety symptoms as risk factors for temporomandibular joint pain: a prospective cohort study in the general population.
Chronic HPA Axis Response to Stress in Temporomandibular Disorder
TLDR
Despite greater perceived stress, TMD cases had lower hair cortisol concentrations than controls and the 2 measures of stress were weakly and negatively correlated.
Associations between symptoms of temporomandibular disorders, quality of life and psychological states in Asian Military Personnel
TLDR
Significant differences in OHRQoL and psychological states were observed between subjects with and without TMD symptoms, and associations between number of T MD symptoms and quality of life, depression, anxiety and stress were significant but weak.
Chronic HPA axis response to stress in temporomandibular disorder.
TLDR
Despite greater perceived stress, TMD cases had lower hair cortisol concentrations than controls and the 2 measures of stress were weakly and negatively correlated.
Chronic HPA axis response to stress in temporomandibular disorder.
TLDR
Despite greater perceived stress, TMD cases had lower hair cortisol concentrations than controls and the 2 measures of stress were weakly and negatively correlated.
The risk of temporomandibular disorder in patients with depression: a population-based cohort study.
TLDR
Patients with depression are at an elevated risk of developing temporomandibular disorder, as demonstrated by a population-based retrospective cohort design.
Psychological correlates of medical comorbidities in patients with temporomandibular disorders.
TLDR
Patients with TMDs who have medical comorbidities may be at increased risk of experiencing poor psychological functioning, and dentists routinely should assess not only the symptoms of their T MDs but also their general health status.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 37 REFERENCES
Craniofacial muscle pain: review of mechanisms and clinical manifestations.
TLDR
The literature in which craniofacial muscle pain has been induced by experimental techniques in animals and human volunteers and in which the effects on somatosensory and motor function have been assessed under standardized conditions is reviewed.
Genetic basis for individual variations in pain perception and the development of a chronic pain condition.
TLDR
Three genetic variants of the gene encoding catecholamine-O-methyltransferase determine COMT activity in humans that inversely correlates with pain sensitivity and the risk of developing TMD.
Genetic origins of anxiety in women: a role for a functional catechol-O-methyltransferase polymorphism
TLDR
The results of the present study suggest that an inherited difference in catecholamine metabolism is important in the pathogenesis of anxiety in women.
A global measure of perceived stress.
TLDR
The Perceived Stress Scale showed adequate reliability and, as predicted, was correlated with life-event scores, depressive and physical symptomatology, utilization of health services, social anxiety, and smoking-reduction maintenance and was a better predictor of the outcome in question than were life- event scores.
COMT val158met Genotype Affects µ-Opioid Neurotransmitter Responses to a Pain Stressor
TLDR
Individuals homozygous for themet158 allele of the catechol-O-methyltransferase (COMT) polymorphism showed diminished regional μ-opioid system responses to pain compared with heterozygotes, and these effects were accompanied by higher sensory and affective ratings of pain and a more negative internal affective state.
A highly significant association between a COMT haplotype and schizophrenia.
TLDR
An efficient approach to gene discovery is reported that found a highly significant association between schizophrenia and a COMT haplotype and can be widely implemented for the genetic dissection of other common diseases.
...
1
2
3
4
...