Influence of Polymorphisms in Innate Immunity Genes on Susceptibility to Invasive Aspergillosis after Stem Cell Transplantation

@inproceedings{Boer2011InfluenceOP,
  title={Influence of Polymorphisms in Innate Immunity Genes on Susceptibility to Invasive Aspergillosis after Stem Cell Transplantation},
  author={Mark G J de Boer and Hetty Jolink and Constantijn J. M. Halkes and Pim L. J. van der Heiden and Dennis Kremer and J H Frederik Falkenburg and Esther van de Vosse and Jaap Tamino van Dissel},
  booktitle={PloS one},
  year={2011}
}
The innate immune system plays a pivotal role in the primary defence against invasive fungal infection. Genetic variation in genes that regulate this response, initiated by pulmonary macrophages, may influence susceptibility to invasive aspergillosis in patients at risk. We investigated in a clinical setting whether common polymorphisms in Toll-like receptor (TLR) and cytokine genes involved in macrophage regulation are associated with susceptibility to invasive aspergillosis. Forty-four… CONTINUE READING
19 Citations
36 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 36 references

Similar Papers

Loading similar papers…