Influence of NaCl concentration at the macula densa on angiotensin II-induced constriction of the afferent arteriole.

@article{Ren1996InfluenceON,
  title={Influence of NaCl concentration at the macula densa on angiotensin II-induced constriction of the afferent arteriole.},
  author={Yilin Ren and Oscar A. Carretero and Sadayoshi Ito},
  journal={Hypertension},
  year={1996},
  volume={27 3 Pt 2},
  pages={649-52}
}
The macula densa, a plaque of specialized tubular epithelial cells, monitors NaCl concentrations in tubular fluid and controls resistance of the glomerular afferent arteriole (AA). In vivo micropuncture studies suggest that there are significant interactions between angiotensin II (Ang II) and macula densa control of glomerular hemodynamics. We tested the hypothesis that Ang II causes stronger constriction of the AA when NaCl concentration at the macula densa is elevated. Rabbit AAs and the… CONTINUE READING

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