Influence of N-acetylcysteine on the formation of biofilm by Staphylococcus epidermidis.

@article{PrezGiraldo1997InfluenceON,
  title={Influence of N-acetylcysteine on the formation of biofilm by Staphylococcus epidermidis.},
  author={Ciro P{\'e}rez-Giraldo and A. Rodr{\'i}guez-Benito and Francisco Javier Tovillas Mor{\'a}n and C{\'e}sar A. Betancur Hurtado and Mar{\'i}a Teresa Blanco and Antonio C{\'a}ndido G{\'o}mez-Garc{\'i}a},
  journal={The Journal of antimicrobial chemotherapy},
  year={1997},
  volume={39 5},
  pages={
          643-6
        }
}
The influence of various concentrations (0.003-8 mg/mL) of N-acetylcysteine on the formation of biofilms by 15 strains of Staphylococcus epidermidis has been studied. A dose-related decrease in biofilm formation was observed, except with the lowest concentrations. The 'slime' index relative to the control was 63%, 55%, 46%, 34%, 26% and 26% in the presence of 0.25, 0.5, 1, 2, 4, and 8 mg/mL of N-acetylcysteine, respectively. These data are statistically significant. The inhibitory effect of 2… CONTINUE READING
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