Influence of Immune Status on the Metastasis of Three Murine Fibrosarcomas of Different Immunogenicities 1

Abstract

Three fibrosarcomas of different ¡mmunogenicities were tested for their ability to form spontaneous and experimentally induced métastasesin normal, sham-suppressed, immunosuppressed, and immunologically restored syngeneic mice. Immunosuppression, achieved by adult thymectomy and sublethal X-irradiation (450 R), affected experimental metastasis of the… (More)

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