Influence of IL-1 gene polymorphism on the periodontal microbiota of HIV-infected Brazilian individuals.

@article{Gonalves2009InfluenceOI,
  title={Influence of IL-1 gene polymorphism on the periodontal microbiota of HIV-infected Brazilian individuals.},
  author={Lucio Souza Gonçalves and Sonia Maria Soares Ferreira and Celso Oliveira Souza and Ana Paula Vieira Colombo},
  journal={Brazilian oral research},
  year={2009},
  volume={23 4},
  pages={452-9}
}
This study investigated the association of IL-1A (+4845) and IL-1B (+3954) gene polymorphism with the subgingival microbiota and periodontal status of HIV-infected Brazilian individuals on highly active antiretroviral therapy (HAART). One hundred and five subjects were included in the study, distributed into 2 HIV groups [29 chronic periodontitis (CP+) and 30 periodontally healthy (H+)]; and 2 non-HIV groups (29 CP- and 17 H- patients). IL-1A and B were genotyped by PCR and restriction enzyme… CONTINUE READING

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