Influence of HLA-DRB1 and TNF microsatellite polymorphisms on the expression of extraarticular manifestations in rheumatoid arthritis patients from northwest Spain.

@article{Mattey2001InfluenceOH,
  title={Influence of HLA-DRB1 and TNF microsatellite polymorphisms on the expression of extraarticular manifestations in rheumatoid arthritis patients from northwest Spain.},
  author={Derek L. Mattey and Miguel A Gonz{\'a}lez-Gay and Carlos Garc{\'i}a-Porr{\'u}a and Wendy Thomson and Ali Hajeer and William E. R. Ollier},
  journal={Clinical and experimental rheumatology},
  year={2001},
  volume={19 6},
  pages={
          703-8
        }
}
OBJECTIVE To determine whether extraarticular manifestations (EAM) in rheumatoid arthritis (RA) patients from northwest (NW) Spain are associated with particular HLA-DRB1 alleles and/or TNF microsatellite polymorphisms. METHODS The frequencies of HLA-DRB1 alleles and TNF microsatellite polymorphisms were compared between RA patients with and without extraarticular disease in a population from Lugo, NW Spain. HLA-DRB1 and TNF typing were carried out using molecular based methods on 181 clinic… CONTINUE READING

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