Influence of HLA-DRB1 allele heterogeneity on disease risk and clinical course in a West Australian MS cohort: a high-resolution genotyping study.

@article{Wu2010InfluenceOH,
  title={Influence of HLA-DRB1 allele heterogeneity on disease risk and clinical course in a West Australian MS cohort: a high-resolution genotyping study.},
  author={Jing-Shan Wu and Ian M James and Wei Qiu and Alison S L Castley and Frank T. Christiansen and William M. Carroll and Francis L Mastaglia and Allan G. Kermode},
  journal={Multiple sclerosis},
  year={2010},
  volume={16 5},
  pages={526-32}
}
BACKGROUND Previous studies on the influence of HLA-DRB1 alleles on multiple sclerosis (MS) susceptibility and clinical course have mostly employed the 2-point genotyping method. OBJECTIVE To assess the influence of HLA-DRB1 alleles and allele interactions on disease risk and clinical course in a large West Australian MS patient cohort using high-resolution genotyping. METHODS Four digit HLA-DRB1 genotyping was performed on a group of 466 clinically definite or probable MS patients from the… CONTINUE READING

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The Busselton Study: mapping population health. Cardiovascular and respiratory disease risk factors in Busselton, Australia

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Highly Influential
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