Influence of HLA-B*5703 and HLA-B*1403 on susceptibility to spondyloarthropathies in the Zambian population.

@article{DazPea2008InfluenceOH,
  title={Influence of HLA-B*5703 and HLA-B*1403 on susceptibility to spondyloarthropathies in the Zambian population.},
  author={Roberto D{\'i}az-Pe{\~n}a and Miguel Angel Blanco-Gelaz and Panganani Njobvu and Antonio L{\'o}pez-V{\'a}zquez and Beatriz Suarez-Alvarez and Carlos L{\'o}pez-Larrea},
  journal={The Journal of rheumatology},
  year={2008},
  volume={35 11},
  pages={
          2236-40
        }
}
OBJECTIVE To analyze the distribution of HLA-B alleles and to investigate their contribution in the susceptibility to spondyloarthropathies (SpA) in a sample population from Zambia, in order to determine a relationship between some HLA-B alleles and development of ankylosing spondylitis (AS), reactive arthritis (ReA), or undifferentiated SpA (uSpA). METHODS . We selected 72 patients with SpA and found that 46 had uSpA, 23 ReA, and 3 AS. We also selected 92 matched controls; 55 of these had… CONTINUE READING

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