Influence of Genetic Variation on Plasma Protein Levels in Older Adults Using a Multi-Analyte Panel

@inproceedings{Kim2013InfluenceOG,
  title={Influence of Genetic Variation on Plasma Protein Levels in Older Adults Using a Multi-Analyte Panel},
  author={Sungeun Kim and Shanker Swaminathan and Mark Inlow and Shannon L. Risacher and Kwangsik Nho and Li Shen and Tatiana Foroud and Ronald C. Petersen and Paul S. Aisen and Holly Soares and Jon B. Toledo and Leslie M. Shaw and John Q. Trojanowski and Michael W Weiner and Brenna C. McDonald and Martin R. Farlow and Bernardino Ghetti and Andrew J. Saykin},
  booktitle={PloS one},
  year={2013}
}
Proteins, widely studied as potential biomarkers, play important roles in numerous physiological functions and diseases. Genetic variation may modulate corresponding protein levels and point to the role of these variants in disease pathophysiology. Effects of individual single nucleotide polymorphisms (SNPs) within a gene were analyzed for corresponding plasma protein levels using genome-wide association study (GWAS) genotype data and proteomic panel data with 132 quality-controlled analytes… CONTINUE READING

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