Influence of Gases on Intraperitoneal Immunity during Laparoscopy in Tumor-bearing Rats

  title={Influence of Gases on Intraperitoneal Immunity during Laparoscopy in Tumor-bearing Rats},
  author={Susan J Neuhaus and David I. Watson and Tanya Ellis and Allan M. Rofe and George G Mathew and G. G. C. Jamieson},
  journal={World Journal of Surgery},
Laparoscopy has been associated with metastases to abdominal wall wounds. In addition, many recent experimental studies suggest that laparoscopy is associated with increased tumor dissemination. It is possible that immune or metabolic disturbances due to the use of a pneumoperitoneum could contribute to this problem. To investigate this possibility, we studied the effect of two insufflation gases and gasless laparoscopy on in vivo peritoneal macrophage function and intraperitoneal pH in an… CONTINUE READING


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