Influence of GSTM1, GSTT1, GSTP1, NAT1, NAT2, EPHX1, MTR and MTHFR polymorphism on chromosomal aberration frequencies in human lymphocytes.

@article{Skjelbred2011InfluenceOG,
  title={Influence of GSTM1, GSTT1, GSTP1, NAT1, NAT2, EPHX1, MTR and MTHFR polymorphism on chromosomal aberration frequencies in human lymphocytes.},
  author={C. Skjelbred and Marit Svendsen and V. Haugan and A. K. Eek and K. O. Clausen and E. Kure and J. Tuimala and M. Svendsen and H. Norppa and Inger-Lise Hansteen},
  journal={Carcinogenesis},
  year={2011},
  volume={32 3},
  pages={
          399-405
        }
}
  • C. Skjelbred, Marit Svendsen, +7 authors Inger-Lise Hansteen
  • Published 2011
  • Biology, Medicine
  • Carcinogenesis
    • We have studied the influence of genetic polymorphisms in the xenobiotic-metabolizing genes GSTM1, GSTP1, GSTT1, EPHX1, NAT1 and NAT2 and the folate-metabolizing genes MTR and MTHFR on the frequencies of cells with chromosomal aberrations (CAs) in peripheral lymphocytes of Norwegian men. Log-linear Poisson regression models were applied on 357 subjects of whom data on all the polymorphisms examined were available. Total CAs and chromosome-type aberrations (CSAs) were significantly increased by… CONTINUE READING
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