Influence of Crystal Habit on the Dissolution of Simvastatin Single Crystals.

Abstract

In order to achieve better in-vivo performance of the final dosage form comprising a poorly soluble drug the physicochemical properties of the active pharmaceutical ingredient can be altered not only by changing the solid state form but also through the conversion of their crystal habits. To elucidate this approach in the case of simvastatin, the… (More)

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Cite this paper

@article{Bukovec2015InfluenceOC, title={Influence of Crystal Habit on the Dissolution of Simvastatin Single Crystals.}, author={Polona Bukovec and Anton Meden and Matej Smrkolj and Franc Vre{\vc}er}, journal={Acta chimica Slovenica}, year={2015}, volume={62 4}, pages={958-66} }