Influence of Childhood Pneumococcal Conjugate Vaccines on Invasive Pneumococcal Disease in Adults With Underlying Comorbidities in Calgary, Alberta (2000-2013).

@article{Cabaj2016InfluenceOC,
  title={Influence of Childhood Pneumococcal Conjugate Vaccines on Invasive Pneumococcal Disease in Adults With Underlying Comorbidities in Calgary, Alberta (2000-2013).},
  author={Jason Lee Cabaj and Alberto Nettel-Aguirre and Judy Macdonald and Otto Gerben Vanderkooi and James Duncan Kellner},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2016},
  volume={62 12},
  pages={1521-6}
}
BACKGROUND Pneumococcal conjugate vaccine (PCV) was introduced into Alberta, Canada's routine childhood immunization programs in 2002 (7-valent [PCV7]) and 2010 (13-valent [PCV13]). We assessed the effect of these programs on the epidemiology of invasive pneumococcal disease (IPD) to determine if PCV-associated indirect protection was relatively reduced in adults with underlying comorbidities. METHODS Demographic and clinical data were collected by a prospective, population-based surveillance… CONTINUE READING
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