Influence of Acanthamoeba castellanii on intracellular growth of different Legionella species in human monocytes.

@article{Neumeister2000InfluenceOA,
  title={Influence of Acanthamoeba castellanii on intracellular growth of different Legionella species in human monocytes.},
  author={Birgid Neumeister and G Reiff and Marion Faigle and Klaus Dietz and Hinnak Northoff and Friederike Lang},
  journal={Applied and environmental microbiology},
  year={2000},
  volume={66 3},
  pages={914-9}
}
Previous studies using a murine model of coinhalation of Legionella pneumophila and Hartmannella vermiformis have shown a significantly enhanced intrapulmonary growth of L. pneumophila in comparison to inhalation of legionellae alone (J. Brieland, M. McClain, L. Heath, C. Chrisp, G. Huffnagle, M. LeGendre, M. Hurley, J. Fantone, and C. Engleberg, Infect. Immun. 64:2449-2456, 1996). In this study, we introduce an in vitro coculture model of legionellae, Mono Mac 6 cells (MM6) and Acanthamoeba… CONTINUE READING

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