Influence of AMP-activated protein kinase and calcineurin on metabolic networks in skeletal muscle.
@article{Long2008InfluenceOA,
title={Influence of AMP-activated protein kinase and calcineurin on metabolic networks in skeletal muscle.},
author={Yun Chau Long and Juleen R. Zierath},
journal={American journal of physiology. Endocrinology and metabolism},
year={2008},
volume={295 3},
pages={
E545-52
}
}Skeletal muscle fibers differ considerably in their metabolic and physiological properties. Skeletal muscle displays a high degree of metabolic flexibility, which allows the myofibers to adapt to various physiological demands by shifting energy substrate utilization. Transcriptional events play a pivotal role in the metabolic adaptations of skeletal muscle. The expression of genes essential for skeletal muscle glucose and lipid metabolism is tightly coordinated in support of a shift in…
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