• DOI:10.1038/201219A0
Corpus ID: 4280113

Influence of 5-Fluorodeoxyuridine on the Cell-infective Unit of Adeno Virus in HeLa Cells

@article{Seto1964InfluenceO5,
  title={Influence of 5-Fluorodeoxyuridine on the Cell-infective Unit of Adeno Virus in HeLa Cells},
  author={Y. Seto and S. Toyoshima and T. Ueda},
  journal={Nature},
  year={1964},
  volume={201},
  pages={219-220}
}

• Y. Seto, S. Toyoshima, T. Ueda
• Published 1964
• Chemistry, Medicine
• Nature

WE have already reported that several halogenated pyrimidines including 5-fluorodeoxyuridine (FUDR) did not show a complete inhibition of the multiplication of adeno type 1 virus in the experiments using the TCID50 estimating dilution method, while vaccinia virus was clearly inhibited with FUDR and some other halogenated pyrimidines1. On the contrary, Flanagan and Ginsberg2 and Green3 reported that FUDR showed clear inhibition during the early phase of the multiplication of adeno type 4 or type… Expand

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