Infliximab in active early rheumatoid arthritis.

  title={Infliximab in active early rheumatoid arthritis.},
  author={Ferdinand C. Breedveld and Paul Emery and Edward Clark Keystone and Kam Patel and Daniel e. Furst and Joachim. R. Kalden and E. William St Clair and Michael H. Weisman and Peter E Lipsky and Ravinder N. Maini},
  journal={Annals of the rheumatic diseases},
  volume={63 2},
OBJECTIVE To examine the impact of the combination of infliximab plus methotrexate (MTX) on the progression of structural damage in patients with early rheumatoid arthritis (RA). METHODS Subanalyses were carried out on data for patients with early RA in the Anti-TNF Therapy in RA with Concomitant Therapy (ATTRACT) study, in which 428 patients with active RA despite MTX therapy received placebo with MTX (MTX-only) or infliximab 3 mg/kg or 10 mg/kg every (q) 4 or 8 weeks with MTX (infliximab… CONTINUE READING
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