Inflammatory status and kynurenine metabolism in rheumatoid arthritis treated with melatonin.

Abstract

AIM Since melatonin is antioxidant and has some anti-inflammatory actions, we have tested it as adjunctive treatment in patients with rheumatoid arthritis, to determine whether it can improve patients' symptoms. METHODS A total of 75 patients were allocated randomly to receive melatonin 10 mg at night in addition to ongoing medication, or a placebo of… (More)

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@article{Forrest2007InflammatorySA, title={Inflammatory status and kynurenine metabolism in rheumatoid arthritis treated with melatonin.}, author={Caroline M. Forrest and Gillian M. Mackay and Nicholas Stoy and Trevor W Stone and L. Gail Darlington}, journal={British journal of clinical pharmacology}, year={2007}, volume={64 4}, pages={517-26} }