Inflammatory responses to implanted polymeric biomaterials: role of surface-adsorbed immunoglobulin G.

@article{Tang1993InflammatoryRT,
  title={Inflammatory responses to implanted polymeric biomaterials: role of surface-adsorbed immunoglobulin G.},
  author={Liping Tang and Alexander H. Lucas and John W. Eaton},
  journal={The Journal of laboratory and clinical medicine},
  year={1993},
  volume={122 3},
  pages={292-300}
}
In many cases, evidently inert and nontoxic biomaterials may trigger procoagulant and inflammatory responses. Because most polymeric biomaterials accumulate a surface layer of protein immediately after implantation, these adverse reactions may stem from secondary interactions between the host and this surface layer of adsorbed proteins. Using polyester terephthalate (the polymer from which both Dacron and Mylar are produced) as a model, we have explored the hypothesis that surface-adsorbed… CONTINUE READING
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