Inflammatory responses and inflammation-associated diseases in organs

@article{Chen2015InflammatoryRA,
  title={Inflammatory responses and inflammation-associated diseases in organs},
  author={Linlin Chen and Huidan Deng and Hengmin Cui and Jing Fang and Zhicai Zuo and Junliang Deng and Yinglun Li and Xun Wang and Ling Zhao},
  journal={Oncotarget},
  year={2015},
  volume={9},
  pages={7204 - 7218}
}
Inflammation is a biological response of the immune system that can be triggered by a variety of factors, including pathogens, damaged cells and toxic compounds. These factors may induce acute and/or chronic inflammatory responses in the heart, pancreas, liver, kidney, lung, brain, intestinal tract and reproductive system, potentially leading to tissue damage or disease. Both infectious and non-infectious agents and cell damage activate inflammatory cells and trigger inflammatory signaling… 
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References

SHOWING 1-10 OF 165 REFERENCES

Innate immune response and hepatic inflammation.

The specificity of Toll-like receptors and the mechanisms of innate immune cell activation are discussed in relation to acute and chronic liver injury including viral, alcoholic, nonalcoholic, and drug-induced hepatitis.

Inflammatory mechanisms: the molecular basis of inflammation and disease.

  • P. Libby
  • Biology, Medicine
    Nutrition reviews
  • 2007
Inflammation participates importantly in host defenses against infectious agents and injury, but it also contributes to the pathophysiology of many chronic diseases. Interactions of cells in the…

T Cells in Vascular Inflammatory Diseases

Evidence supporting the role of different T cell subsets in vascular inflammation is described and selected targeting of pathogenic TEM cells might enable a more tailored therapeutic approach that avoids unwanted adverse side effects of generalized immunosuppression.

STAT6 and lung inflammation

This review will focus on the role of STAT6 in lung diseases and mechanisms by which STAT6 controls immune and structural lung cell function.

MAPK signalling pathways as molecular targets for anti-inflammatory therapy--from molecular mechanisms to therapeutic benefits.

Key mechanisms governing resolution of lung inflammation

This review will summarise the major mechanisms regulating lung inflammation, including key cellular interplays such as apoptotic cell clearance by alveolar macrophages and macrophage/neutrophil/epithelial cell interactions.

Innate immune recognition in infectious and noninfectious diseases of the lung.

The PRR engagement is the prerequisite for the initiation of immune responses to infections and tissue injuries which can be beneficial or detrimental to the host.

Decoding cell death signals in liver inflammation.

Inflammatory pathways in female reproductive health and disease.

The role of inflammatory events in normal reproductive function and its pathologies is addressed and specific biochemical events are activated to re-establish homeostasis in the affected tissue.

Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responses.

  • A. Beg
  • Biology
    Trends in immunology
  • 2002
...