Inflammatory profiles in canine intervertebral disc degeneration

  title={Inflammatory profiles in canine intervertebral disc degeneration},
  author={Nicole Willems and Anna R. Tellegen and Niklas Bergknut and Laura B. Creemers and Jeannette Wolfswinkel and Christian Freudigmann and Karin Benz and Guy C. M. Grinwis and Marianna A Tryfonidou and Bj{\"o}rn Petrus Meij},
  booktitle={BMC veterinary research},
BACKGROUND Intervertebral disc (IVD) disease is a common spinal disorder in dogs and degeneration and inflammation are significant components of the pathological cascade. Only limited studies have studied the cytokine and chemokine profiles in IVD degeneration in dogs, and mainly focused on gene expression. A better understanding is needed in order to develop biological therapies that address both pain and degeneration in IVD disease. Therefore, in this study, we determined the levels of… CONTINUE READING